Distribution of restriction sites in the human genome

Enzyme:  NspV               Longest uncut segments
Specificity:  TTCGAA               Repeats in uncut segments
Number of sites:  105070               Genes in uncut segments
Mean distance between sites:  27232 base pairs
Standard deviation:  28088 base pairs
Site density 36.7 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   516074  chr15  NT_037852.6  1398403-1914477    1.92 % in   46 repeats    1.93 % in 1 genes
2   451729  chr6  NT_167244.1  2338469-2790198    5.52 % in   99 repeats    3.00 % in 2 genes
3   437031  chrY  NT_011875.12  8354113-8791144    80.34 % in   221 repeats    0.45 % in 3 genes
4   383109  chr1  NT_004350.19  1824554-2207663    16.75 % in   280 repeats    67.48 % in 10 genes
5   348512  chrY  NT_011875.12  337594-686106    65.59 % in   700 repeats    11.53 % in 5 genes
6   342508  chr4  NT_016354.19  80307263-80649771    58.26 % in   552 repeats    0.00 % in 0 genes
7   337550  chr6  NT_167244.1  1995519-2333069    16.08 % in   196 repeats    8.64 % in 6 genes
8   330722  chr13  NT_009952.14  11512451-11843173    58.35 % in   764 repeats    21.54 % in 2 genes
9   327049  chr6  NT_167244.1  3039544-3366593    17.76 % in   290 repeats    0.00 % in 0 genes
10   326497  chr11  NT_009237.18  49612773-49939270    53.43 % in   462 repeats    0.00 % in 0 genes
11   310036  chrY  NT_011896.9  5824992-6135028    33.19 % in   388 repeats    0.00 % in 0 genes
12   303493  chr6  NT_007299.13  224644-528137    51.97 % in   283 repeats    0.00 % in 0 genes
13   303094  chr5  NT_006713.15  7018875-7321969    57.25 % in   680 repeats    0.00 % in 0 genes
14   302969  chr7  NT_007933.15  47595102-47898071    59.80 % in   455 repeats    0.00 % in 0 genes
15   300085  chr5  NT_006713.15  9410338-9710423    34.62 % in   466 repeats    0.00 % in 0 genes
16   294474  chr7  NT_007933.15  56711772-57006246    60.14 % in   440 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
516074  chr15  NT_037852.6  1398403-1914477    46  27       AT_rich (5)  L2a (4)  (TA)n (3) 
451729  chr6  NT_167244.1  2338469-2790198    99  53       AluY (7)  AluSx (5)  AluJb (5) 
437031  chrY  NT_011875.12  8354113-8791144    221  87       AT_rich (20)  LTR12B (17)  AluY (11) 
383109  chr1  NT_004350.19  1824554-2207663    280  99       MIRb (17)  AluSx (17)  MIR (13) 
348512  chrY  NT_011875.12  337594-686106    700  201       AluSx (54)  AluJo (48)  AT_rich (26) 
342508  chr4  NT_016354.19  80307263-80649771    552  208       AT_rich (38)  MIRb (19)  L2a (18) 
337550  chr6  NT_167244.1  1995519-2333069    196  73       AluSx (24)  MIR (10)  AluSp (8) 
330722  chr13  NT_009952.14  11512451-11843173    764  202       AluSx (88)  AT_rich (31)  AluY (25) 
327049  chr6  NT_167244.1  3039544-3366593    290  67       AluSx (45)  AluY (18)  AluJo (16) 
10  326497  chr11  NT_009237.18  49612773-49939270    462  157       AT_rich (42)  MIRb (24)  L2a (23) 
11  310036  chrY  NT_011896.9  5824992-6135028    388  111       SST1 (60)  (CA)n (30)  AT_rich (25) 
12  303493  chr6  NT_007299.13  224644-528137    283  115       AT_rich (22)  ALR/Alpha (16)  MIR (13) 
13  303094  chr5  NT_006713.15  7018875-7321969    680  174       AluSx (75)  AluJb (38)  AluSq (33) 
14  302969  chr7  NT_007933.15  47595102-47898071    455  167       AT_rich (34)  L2c (15)  MIRb (13) 
15  300085  chr5  NT_006713.15  9410338-9710423    466  135       AT_rich (40)  MIRb (31)  L2a (27) 
16  294474  chr7  NT_007933.15  56711772-57006246    440  162       AT_rich (42)  (TA)n (16)  AluSx (13) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
1   516074       chr15  NT_037852.6  1398403-1914477    LOC100418897 
2   451729       chr6  NT_167244.1  2338469-2790198    HCG22  HLA_complex_group_22
MICB  MHC_class_I_polypeptide-related_sequence_B_precursor
3   437031       chrY  NT_011875.12  8354113-8791144    ZNF886P 
ZNF884P 
ZNF885P 
4   383109       chr1  NT_004350.19  1824554-2207663    PLCH2  1-phosphatidylinositol-4,5-bisphosphate_phosphodiesterase_eta-2
PANK4  pantothenate_kinase_4
HES5  transcription_factor_HES-5
LOC115110  hypothetical_LOC115110
LOC100133445  hypothetical_LOC100133445
TNFRSF14  tumor_necrosis_factor_receptor_superfamily_member_14_precursor
LOC100506589  hypothetical_LOC100506589
C1orf93  hypothetical_protein_LOC127281_isoform_b
MMEL1  membrane_metallo-endopeptidase-like_1
TTC34  tetratricopeptide_repeat_protein_34
5   348512       chrY  NT_011875.12  337594-686106    RPS24P1 
ARSFP1 
FAM8A8P 
ARSEP1 
ARSDP1 
7   337550       chr6  NT_167244.1  1995519-2333069    MDC1  mediator_of_DNA_damage_checkpoint_protein_1
LOC100294090  hypothetical_LOC100294090,_transcript_variant_1
FLOT1  flotillin-1
DDR1  epithelial_discoidin_domain-containing_receptor_1_isoform_DDR1c
MUC21  mucin-21_precursor
LOC100507702  hypothetical_protein_LOC100507702
8   330722       chr13  NT_009952.14  11512451-11843173    RPL7AP61 
FTLP8  importin-5



Posfai@neb.com
May 11, 2011