Distribution of restriction sites in the human genome

Enzyme:  SnaBI               Longest uncut segments
Specificity:  TACGTA               Repeats in uncut segments
Number of sites:  127210               Genes in uncut segments
Mean distance between sites:  22493 base pairs
Standard deviation:  25247 base pairs
Site density 44.5 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


Help
Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   523748  chr15  NT_037852.6  1372768-1896516    4.60 % in   78 repeats    0.66 % in 1 genes
2   458483  chr6  NT_167244.1  2324300-2782783    5.97 % in   122 repeats    1.72 % in 2 genes
3   415199  chr22  NT_011520.12  22052407-22467606    51.37 % in   1094 repeats    42.76 % in 10 genes
4   396041  chr9  NT_019501.13  463155-859196    33.60 % in   513 repeats    49.85 % in 3 genes
5   359069  chrX  NT_079573.4  1978709-2337778    51.22 % in   679 repeats    0.00 % in 0 genes
6   355751  chr19  NT_011109.16  21737882-22093633    56.00 % in   906 repeats    66.36 % in 31 genes
7   354882  chr6  NT_167244.1  3078065-3432947    15.89 % in   270 repeats    21.81 % in 11 genes
8   334449  chr6  NT_007592.15  37334541-37668990    42.74 % in   698 repeats    41.00 % in 5 genes
9   318187  chr11  NT_009237.18  967745-1285932    24.60 % in   311 repeats    0.00 % in 0 genes
10   311166  chr19  NT_011295.11  10381920-10693086    52.76 % in   827 repeats    0.00 % in 0 genes
11   310742  chr20  NT_011362.10  1239512-1550254    51.16 % in   857 repeats    0.00 % in 0 genes
12   309932  chr6  NT_167244.1  3743371-4053303    20.42 % in   219 repeats    0.00 % in 0 genes
13   305883  chr6  NT_167244.1  1981239-2287122    10.49 % in   137 repeats    0.00 % in 0 genes
14   303830  chr6  NT_167246.1  3157224-3461054    15.46 % in   204 repeats    0.00 % in 0 genes
15   303493  chr1  NT_032977.9  802296-1105789    56.61 % in   599 repeats    0.00 % in 0 genes
16   303235  chr6  NT_167246.1  2192747-2495982    40.99 % in   523 repeats    0.00 % in 0 genes


Help
Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
523748  chr15  NT_037852.6  1372768-1896516    78  42       Tigger2 (6)  L1ME3C (6)  L1MDa (6) 
458483  chr6  NT_167244.1  2324300-2782783    122  57       AluSx (8)  AluJo (8)  L1MC4a (7) 
415199  chr22  NT_011520.12  22052407-22467606    1094  178       AluSx (140)  MIRb (80)  MIR (53) 
396041  chr9  NT_019501.13  463155-859196    513  158       AluSx (26)  MIRc (24)  MIRb (22) 
359069  chrX  NT_079573.4  1978709-2337778    679  174       MIR (46)  MIRb (39)  L2c (33) 
355751  chr19  NT_011109.16  21737882-22093633    906  156       AluSx (140)  AluY (59)  AluJb (45) 
354882  chr6  NT_167244.1  3078065-3432947    270  60       AluSx (45)  AluSq (16)  AluJo (16) 
334449  chr6  NT_007592.15  37334541-37668990    698  149       MIR (54)  MIRb (48)  AluSx (48) 
318187  chr11  NT_009237.18  967745-1285932    311  112       AluSx (30)  L1M5 (12)  GC_rich (11) 
10  311166  chr19  NT_011295.11  10381920-10693086    827  121       AluSx (143)  AluJo (77)  AluJb (50) 
11  310742  chr20  NT_011362.10  1239512-1550254    857  125       AluSx (91)  MIR (68)  MIRb (62) 
12  309932  chr6  NT_167244.1  3743371-4053303    219  109       L2a (18)  AT_rich (15)  AluY (7) 
13  305883  chr6  NT_167244.1  1981239-2287122    137  58       AluSx (18)  MIR (7)  AluSg (7) 
14  303830  chr6  NT_167246.1  3157224-3461054    204  65       AluSx (32)  AluSq (11)  AluJb (10) 
15  303493  chr1  NT_032977.9  802296-1105789    599  150       MIR (79)  MIRb (75)  L2b (46) 
16  303235  chr6  NT_167246.1  2192747-2495982    523  143       AluSx (55)  AluJb (29)  AluSq (24) 


Help
Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
1   523748       chr15  NT_037852.6  1372768-1896516    LOC100418897 
2   458483       chr6  NT_167244.1  2324300-2782783    HCG22  HLA_complex_group_22
MICB  MHC_class_I_polypeptide-related_sequence_B_precursor
3   415199       chr22  NT_011520.12  22052407-22467606    LOC388906  hypothetical_LOC388906
LOC100134361  hypothetical_LOC100134361,_transcript_variant_3
NFAM1  NFAT_activation_molecule_1_precursor
LOC100506662  hypothetical_LOC100506662
RRP7A  ribosomal_RNA-processing_protein_7_homolog_A
SERHL2  serine_hydrolase-like_protein_2
RRP7B  ribosomal_RNA_processing_7_homolog_B_(S._cerevisiae)
POLDIP3  polymerase_delta-interacting_protein_3_isoform_2
RNU12  RNA,_U12_small_nuclear
ATP5L2  ATP_synthase_subunit_g_2,_mitochondrial
4   396041       chr9  NT_019501.13  463155-859196    LOC100506554  hypothetical_LOC100506554
FCN2  ficolin-2_isoform_b_precursor
FCN1  ficolin-1_precursor
6   355751       chr19  NT_011109.16  21737882-22093633    FTL  ferritin_light_chain
GYS1  glycogen_[starch]_synthase,_muscle_isoform_2
RUVBL2  ruvB-like_2
LHB  lutropin_subunit_beta_precursor
LOC100287421  hypothetical_protein_LOC100287421
CGB  choriogonadotropin_subunit_beta_precursor
NTF6A 
NTF6G 
SNAR-G2  small_ILF3/NF90-associated_RNA_G2
CGB2  choriogonadotropin_subunit_beta_variant_2
CGB1  choriogonadotropin_subunit_beta_variant_1
SNAR-G1  small_ILF3/NF90-associated_RNA_G1
NTF6B 
LOC100287453 
CGB5  chorionic_gonadotropin,_beta_polypeptide_5_precursor
LOC100505886  hypothetical_LOC100505886
CGB8  chorionic_gonadotropin,_beta_polypeptide_8_precursor
LOC100287489 
CGB7  chorionic_gonadotropin,_beta_polypeptide_7_precursor
LOC100287526  hypothetical_protein_LOC100287526
NTF4  neurotrophin-4_preproprotein
KCNA7  potassium_voltage-gated_channel_subfamily_A_member_7
SNRNP70  U1_small_nuclear_ribonucleoprotein_70_kDa
LIN7B  protein_lin-7_homolog_B
C19orf73  putative_uncharacterized_protein_C19orf73
PPFIA3  liprin-alpha-3
HRC  sarcoplasmic_reticulum_histidine-rich_calcium-binding_protein_precursor
TRPM4  transient_receptor_potential_cation_channel_subfamily_M_member_4_isoform_1
SLC6A21P 
SUMO1P4 
MIR4324  microRNA_4324
7   354882       chr6  NT_167244.1  3078065-3432947    VARS  valyl-tRNA_synthetase
LSM2  U6_snRNA-associated_Sm-like_protein_LSm2
HSPA1L  heat_shock_70_kDa_protein_1-like
HSPA1A  heat_shock_70_kDa_protein_1A/1B
HSPA1B  heat_shock_70_kDa_protein_1A/1B
C6orf48  protein_G8
NEU1  sialidase-1_precursor
SLC44A4  choline_transporter-like_protein_4_isoform_3
EHMT2  histone-lysine_N-methyltransferase,_H3_lysine-9_specific_3_isoform_b
TNXB  tenascin-X_isoform_1_precursor
PRRT1  proline-rich_transmembrane_protein_1
8   334449       chr6  NT_007592.15  37334541-37668990    FTSJD2  cap-specific_mRNA_(nucleoside-2'-O-)-methyltransferase_1
C6orf129  transmembrane_and_coiled-coil_domain-containing_protein_C6orf129
LOC100505530  hypothetical_LOC100505530
LOC100505550  hypothetical_LOC100505550
MDGA1  MAM_domain-containing_glycosylphosphatidylinositol_anchor_protein_1_precursor



Posfai@neb.com
May 11, 2011