Distribution of restriction sites in the human genome

Enzyme:  DrdIV               Longest uncut segments
Specificity:  TACGAC               Repeats in uncut segments
Number of sites:  86033               Genes in uncut segments
Mean distance between sites:  33258 base pairs
Standard deviation:  34457 base pairs
Site density 30.1 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   638043  chr15  NT_037852.6  1267796-1905839    13.57 % in   368 repeats    2.67 % in 2 genes
2   602813  chr6  NT_167244.1  2281605-2884418    14.38 % in   343 repeats    8.32 % in 11 genes
3   458601  chrY  NT_011878.9  1-458602    35.58 % in   533 repeats    26.62 % in 22 genes
4   392877  chr3  NT_022517.18  10529194-10922071    46.46 % in   841 repeats    32.31 % in 2 genes
5   385701  chr12  NT_029419.12  272497-658198    92.25 % in   228 repeats    2.76 % in 1 genes
6   372929  chr17  NT_010799.15  2268020-2640949    58.61 % in   998 repeats    58.52 % in 9 genes
7   372805  chr11  NT_167190.1  3806761-4179566    65.12 % in   533 repeats    64.29 % in 7 genes
8   361749  chr1  NT_004487.19  3369375-3731124    48.92 % in   644 repeats    17.18 % in 11 genes
9   360979  chr6  NT_167249.1  2043520-2404499    23.96 % in   364 repeats    0.00 % in 0 genes
10   358323  chrX  NT_011669.17  1744075-2102398    76.72 % in   527 repeats    0.00 % in 0 genes
11   357937  chrX  NT_011669.17  8028808-8386745    76.85 % in   666 repeats    0.00 % in 0 genes
12   353563  chr9  NT_008413.18  7469738-7823301    53.96 % in   584 repeats    0.00 % in 0 genes
13   325193  chr1  NT_004610.19  13380588-13705781    59.55 % in   961 repeats    0.00 % in 0 genes
14   315708  chr1  NT_032977.9  90462165-90777873    32.48 % in   451 repeats    0.00 % in 0 genes
15   314807  chr6  NT_167244.1  1951696-2266503    9.79 % in   152 repeats    0.00 % in 0 genes
16   313043  chr11  NT_009237.18  50312025-50625068    97.98 % in   91 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
638043  chr15  NT_037852.6  1267796-1905839    368  111       AluSx (24)  AT_rich (13)  AluJb (13) 
602813  chr6  NT_167244.1  2281605-2884418    343  108       AluSx (41)  AluJo (20)  AluJb (16) 
458601  chrY  NT_011878.9  1-458602    533  110       AT_rich (47)  (TG)n (45)  SST1 (44) 
392877  chr3  NT_022517.18  10529194-10922071    841  175       MIRb (107)  MIR (80)  L2b (57) 
385701  chr12  NT_029419.12  272497-658198    228  78       ALR/Alpha (45)  AluY (11)  AluSg (11) 
372929  chr17  NT_010799.15  2268020-2640949    998  159       AluSx (166)  AluJb (85)  AluY (66) 
372805  chr11  NT_167190.1  3806761-4179566    533  142       MIR (31)  MIRb (21)  AT_rich (21) 
361749  chr1  NT_004487.19  3369375-3731124    644  195       L2c (47)  AluSx (32)  MIR (27) 
360979  chr6  NT_167249.1  2043520-2404499    364  111       AluSx (41)  AluJb (25)  AluJo (15) 
10  358323  chrX  NT_011669.17  1744075-2102398    527  138       L2a (23)  AluJo (22)  L2c (20) 
11  357937  chrX  NT_011669.17  8028808-8386745    666  160       AluSx (59)  AT_rich (23)  AluJb (19) 
12  353563  chr9  NT_008413.18  7469738-7823301    584  181       MIRb (50)  L2c (30)  MIRc (22) 
13  325193  chr1  NT_004610.19  13380588-13705781    961  136       AluSx (135)  AluJb (69)  MIRb (60) 
14  315708  chr1  NT_032977.9  90462165-90777873    451  118       MIRb (38)  L2c (31)  L2a (30) 
15  314807  chr6  NT_167244.1  1951696-2266503    152  50       AluSx (23)  AluJb (11)  AluY (8) 
16  313043  chr11  NT_009237.18  50312025-50625068    91  31       ALR/Alpha (34)  L1PA4 (7)  MER11C (6) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
1   638043       chr15  NT_037852.6  1267796-1905839    LOC727914 
LOC100418897 
2   602813       chr6  NT_167244.1  2281605-2884418    LOC100507702  hypothetical_protein_LOC100507702
HCG22  HLA_complex_group_22
MICB  MHC_class_I_polypeptide-related_sequence_B_precursor
PPIAP9 
RPL15P4 
MCCD1  mitochondrial_coiled-coil_domain_protein_1_precursor
SNORD117  small_nucleolar_RNA,_C/D_box_117
TNF  tumor_necrosis_factor
LTB  lymphotoxin-beta_isoform_b
LST1  leukocyte-specific_transcript_1_protein_isoform_5
NCR3  natural_cytotoxicity_triggering_receptor_3_isoform_c
3   458601       chrY  NT_011878.9  1-458602    FAM197Y5  testis-specific_Y-encoded_protein_1-like
TSPY1  testis-specific_Y-encoded_protein_1_isoform_TSPY-L
FAM197Y4  testis-specific_Y-encoded_protein_1-like
TSPY9 
FAM197Y3  testis-specific_Y-encoded_protein_1-like
TSPY6P 
FAM197Y2P  family_with_sequence_similarity_197,_Y-linked,_member_2,_pseudogene
TSPY10  testis-specific_Y-encoded_protein_1-like_isoform_2
FAM197Y1  hypothetical_protein_LOC100289265
TSPY15P 
RBMY3AP  RNA_binding_motif_protein,_Y-linked,_family_3,_member_A_pseudogene
TSPY16P 
TTTY8  testis-specific_transcript,_Y-linked_8_(non-protein_coding)
TTTY7B  testis-specific_transcript,_Y-linked_7B_(non-protein_coding)
TTTY21  testis-specific_transcript,_Y-linked_21_(non-protein_coding)
TTTY2  testis-specific_transcript,_Y-linked_2_(non-protein_coding)
TTTY1  testis-specific_transcript,_Y-linked_1_(non-protein_coding)
TTTY22  testis-specific_transcript,_Y-linked_22_(non-protein_coding)
RBMY2NP 
TSPY18P 
TSPY13P 
TTTY23  testis-specific_transcript,_Y-linked_23_(non-protein_coding)
4   392877       chr3  NT_022517.18  10529194-10922071    LOC285370  hypothetical_LOC285370
SLC6A11  sodium-_and_chloride-dependent_GABA_transporter_3
5   385701       chr12  NT_029419.12  272497-658198    LOC100128817 
6   372929       chr17  NT_010799.15  2268020-2640949    TWF1P1 
CRYBA1  beta-crystallin_A3
NUFIP2  nuclear_fragile_X_mental_retardation-interacting_protein_2
RPL35AP35 
TAOK1  serine/threonine-protein_kinase_TAO1
LOC100506461  hypothetical_LOC100506461
ABHD15  abhydrolase_domain-containing_protein_15_precursor
TP53I13  tumor_protein_p53-inducible_protein_13_precursor
GIT1  ARF_GTPase-activating_protein_GIT1_isoform_2
7   372805       chr11  NT_167190.1  3806761-4179566    LOC100420019 
LOC100101405 
GLYATL2  glycine_N-acyltransferase-like_protein_2
GLYATL1P2 
LOC100287485  glycine_N-acyltransferase-like_protein_1
GLYATL1P4  glycine-N-acyltransferase-like_1_pseudogene_4_isoform_3
GLYATL1P3 
8   361749       chr1  NT_004487.19  3369375-3731124    THEM4  thioesterase_superfamily_member_4
KRT8P28 
S100A10  protein_S100-A10
NBPF18P 
S100A11  protein_S100-A11
LOC100131107  putative_UPF0607_protein_ENSP00000383783
TCHHL1  trichohyalin-like_protein_1
TCHH  trichohyalin
HDHD1P2 
RPTN  repetin
HRNR  hornerin



Posfai@neb.com
May 11, 2011