Distribution of restriction sites in the human genome

Enzyme:  Bme1580I               Longest uncut segments
Specificity:  GKGCMC               Repeats in uncut segments
Number of sites:  1980555               Genes in uncut segments
Mean distance between sites:  1444 base pairs
Standard deviation:  1899 base pairs
Site density 692.2 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   494116  chr15  NT_037852.6  1397287-1891403    0.76 % in   17 repeats    0.00 % in 0 genes
2   404388  chr6  NT_167244.1  2357133-2761521    0.55 % in   9 repeats    0.00 % in 0 genes
3   211309  chr6  NT_167244.1  4388443-4599752    1.38 % in   12 repeats    0.00 % in 0 genes
4   184299  chr6  NT_167244.1  3787279-3971578    0.96 % in   10 repeats    0.12 % in 1 genes
5   175288  chr6  NT_167244.1  3180070-3355358    0.09 % in   4 repeats    0.09 % in 1 genes
6   172796  chr6  NT_167247.1  4421857-4594653    0.23 % in   2 repeats    100.00 % in 1 genes
7   168582  chr6  NT_167249.1  2136128-2304710    1.52 % in   14 repeats    0.00 % in 0 genes
8   164328  chr6  NT_167247.1  1562903-1727231    0.01 % in   1 repeats    0.03 % in 1 genes
9   163318  chr6  NT_167248.1  520515-683833    2.45 % in   2 repeats    0.00 % in 0 genes
10   151609  chr9  NT_008470.19  21692392-21844001    0.48 % in   3 repeats    0.00 % in 0 genes
11   146962  chr6  NT_167244.1  2892551-3039513    2.10 % in   16 repeats    0.00 % in 0 genes
12   134942  chrY  NT_011875.12  8518392-8653334    62.89 % in   6 repeats    0.00 % in 0 genes
13   127581  chr1  NT_077389.3  263997-391578    99.17 % in   57 repeats    0.00 % in 0 genes
14   119203  chr6  NT_167245.1  2605070-2724273    1.36 % in   3 repeats    0.00 % in 0 genes
15   116173  chr6  NT_167247.1  1176165-1292338    1.29 % in   2 repeats    0.00 % in 0 genes
16   115450  chr6  NT_167246.1  3259651-3375101    0.49 % in   3 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
494116  chr15  NT_037852.6  1397287-1891403    17  14       L2a (3)  L1M5 (2)  U2 (1) 
404388  chr6  NT_167244.1  2357133-2761521    7       L4 (2)  AluJb (2)  MER8 (1) 
211309  chr6  NT_167244.1  4388443-4599752    12  10       MER57-int (2)  AluSx (2)  (TTCC)n (1) 
184299  chr6  NT_167244.1  3787279-3971578    10  9       AT_rich (2)  MLT1H-int (1)  MIR (1) 
175288  chr6  NT_167244.1  3180070-3355358    3       GC_rich (2)  (CCG)n (1)  AluSp (1) 
172796  chr6  NT_167247.1  4421857-4594653    2       MER11A (1)  AluSc (1) 
168582  chr6  NT_167249.1  2136128-2304710    14  9       AluSx (4)  L1MB8 (3)  MLT1A (1) 
164328  chr6  NT_167247.1  1562903-1727231    1       MIR (1) 
163318  chr6  NT_167248.1  520515-683833    2       L1PREC2 (1)  HERVH-int (1) 
10  151609  chr9  NT_008470.19  21692392-21844001    3       MIR3 (1)  LTR67B (1)  L1M5 (1) 
11  146962  chr6  NT_167244.1  2892551-3039513    16  9       L1MC5 (4)  AluSc (3)  AluY (2) 
12  134942  chrY  NT_011875.12  8518392-8653334    1       LTR12B (6) 
13  127581  chr1  NT_077389.3  263997-391578    57  5       ALR/Alpha (52)  MLT1J (2)  L2 (1) 
14  119203  chr6  NT_167245.1  2605070-2724273    3       MLT1E2 (1)  L2a (1)  L2 (1) 
15  116173  chr6  NT_167247.1  1176165-1292338    1       ERV3-16A3_I-int (2) 
16  115450  chr6  NT_167246.1  3259651-3375101    3       MIRb (1)  MIR3 (1)  AluSx (1) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
4   184299       chr6  NT_167244.1  3787279-3971578    HLA-DRB3  major_histocompatibility_complex,_class_II,_DR_beta_3_precursor
5   175288       chr6  NT_167244.1  3180070-3355358    EHMT2  histone-lysine_N-methyltransferase,_H3_lysine-9_specific_3_isoform_b
6   172796       chr6  NT_167247.1  4421857-4594653    LOC100507722  hypothetical_protein_LOC100507722
8   164328       chr6  NT_167247.1  1562903-1727231    LOC100421582  tripartite_motif-containing_protein_26



Posfai@neb.com
May 11, 2011