Distribution of restriction sites in the human genome

Enzyme:  R2.BsrDI               Longest uncut segments
Specificity:  GCAATG               Repeats in uncut segments
Number of sites:  1413826               Genes in uncut segments
Mean distance between sites:  2023 base pairs
Standard deviation:  2077 base pairs
Site density 494.1 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   488514  chr15  NT_037852.6  1398227-1886741    0.01 % in   1 repeats    0.00 % in 0 genes
2   404672  chr6  NT_167244.1  2358595-2763267    0.31 % in   5 repeats    0.00 % in 0 genes
3   210350  chr6  NT_167244.1  4388242-4598592    1.16 % in   8 repeats    0.00 % in 0 genes
4   181885  chr6  NT_167244.1  3790357-3972242    0.78 % in   7 repeats    0.00 % in 0 genes
5   177148  chr6  NT_167247.1  4420242-4597390    1.47 % in   12 repeats    100.00 % in 1 genes
6   175346  chr6  NT_167244.1  3180100-3355446    0.13 % in   3 repeats    0.07 % in 1 genes
7   172655  chr6  NT_167247.1  1554932-1727587    2.72 % in   23 repeats    4.65 % in 1 genes
8   167496  chr6  NT_167249.1  2137917-2305413    1.13 % in   9 repeats    0.00 % in 0 genes
9   161485  chr6  NT_167244.1  2005917-2167402    1.73 % in   14 repeats    0.00 % in 0 genes
10   160277  chr6  NT_167248.1  521312-681589    0.60 % in   2 repeats    0.00 % in 0 genes
11   153990  chr9  NT_008470.19  21689731-21843721    1.81 % in   8 repeats    0.00 % in 0 genes
12   143361  chr6  NT_167244.1  2894368-3037729    0.23 % in   4 repeats    0.00 % in 0 genes
13   124389  chrX  NT_011786.16  4267037-4391426    10.20 % in   72 repeats    0.00 % in 0 genes
14   124362  chr6  NT_167245.1  2600187-2724549    4.54 % in   15 repeats    0.00 % in 0 genes
15   118330  chr6  NT_167247.1  1175890-1294220    1.50 % in   2 repeats    0.00 % in 0 genes
16   116819  chr6  NT_167246.1  3259241-3376060    0.73 % in   6 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
488514  chr15  NT_037852.6  1398227-1886741    1       AT_rich (1) 
404672  chr6  NT_167244.1  2358595-2763267    4       AluJb (2)  L4 (1)  L1MEg (1) 
210350  chr6  NT_167244.1  4388242-4598592    7       MER57-int (2)  (TTCC)n (1)  L1MC (1) 
181885  chr6  NT_167244.1  3790357-3972242    6       MLT1H-int (2)  MLT1H (1)  MER52D (1) 
177148  chr6  NT_167247.1  4420242-4597390    12  11       MLT1J (2)  (TTAAA)n (1)  MIR (1) 
175346  chr6  NT_167244.1  3180100-3355446    3       GC_rich (1)  (CCG)n (1)  AluSp (1) 
172655  chr6  NT_167247.1  1554932-1727587    23  19       L2c (3)  Tigger7 (2)  MSTD (2) 
167496  chr6  NT_167249.1  2137917-2305413    5       L1MB8 (3)  AluSx (3)  L1MC4a (1) 
161485  chr6  NT_167244.1  2005917-2167402    14  10       AluSx (4)  AluJb (2)  MIRb (1) 
10  160277  chr6  NT_167248.1  521312-681589    2       L1PREC2 (1)  HERVH-int (1) 
11  153990  chr9  NT_008470.19  21689731-21843721    6       LTR67B (2)  L1M4b (2)  MSTA (1) 
12  143361  chr6  NT_167244.1  2894368-3037729    4       L1MC5 (1)  AluY (1)  AluSg1 (1) 
13  124389  chrX  NT_011786.16  4267037-4391426    72  20       AluSx (15)  MER33 (14)  AluSc (13) 
14  124362  chr6  NT_167245.1  2600187-2724549    15  12       MLT1N2 (2)  MER21C (2)  L2 (2) 
15  118330  chr6  NT_167247.1  1175890-1294220    1       ERV3-16A3_I-int (2) 
16  116819  chr6  NT_167246.1  3259241-3376060    5       MIRb (2)  MIR3 (1)  L2a (1) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
5   177148       chr6  NT_167247.1  4420242-4597390    LOC100507722  hypothetical_protein_LOC100507722
6   175346       chr6  NT_167244.1  3180100-3355446    EHMT2  histone-lysine_N-methyltransferase,_H3_lysine-9_specific_3_isoform_b
7   172655       chr6  NT_167247.1  1554932-1727587    LOC100421582  tripartite_motif-containing_protein_26



Posfai@neb.com
May 11, 2011