Distribution of restriction sites in the human genome

Enzyme:  ZraI               Longest uncut segments
Specificity:  GACGTC               Repeats in uncut segments
Number of sites:  69719               Genes in uncut segments
Mean distance between sites:  41041 base pairs
Standard deviation:  50398 base pairs
Site density 24.4 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   1016518  chr12  NT_029419.12  36144301-37160819    56.85 % in   1655 repeats    16.29 % in 4 genes
2   824351  chrX  NT_011651.17  787845-1612196    74.16 % in   1042 repeats    10.38 % in 7 genes
3   696592  chr6  NT_025741.15  6808601-7505193    56.68 % in   1088 repeats    0.00 % in 0 genes
4   609742  chr5  NT_023133.13  10123324-10733066    46.25 % in   1012 repeats    0.29 % in 3 genes
5   609400  chr4  NT_006238.11  5673403-6282803    50.32 % in   977 repeats    37.54 % in 2 genes
6   589458  chr1  NT_004487.19  25777141-26366599    56.77 % in   1017 repeats    100.00 % in 1 genes
7   582842  chr3  NT_005612.16  72425828-73008670    55.41 % in   900 repeats    0.09 % in 1 genes
8   571106  chr3  NT_005612.16  71359277-71930383    53.07 % in   968 repeats    1.74 % in 1 genes
9   566260  chr15  NT_037852.6  1339256-1905516    7.53 % in   164 repeats    0.00 % in 0 genes
10   561568  chr6  NT_025741.15  44836994-45398562    57.37 % in   929 repeats    0.00 % in 0 genes
11   545960  chr2  NT_005403.17  37121352-37667312    56.95 % in   906 repeats    0.00 % in 0 genes
12   542922  chr10  NT_030059.13  60464560-61007482    52.05 % in   870 repeats    0.00 % in 0 genes
13   540922  chr12  NT_029419.12  62146475-62687397    62.31 % in   1087 repeats    0.00 % in 0 genes
14   531120  chr6  NT_007299.13  9995305-10526425    47.68 % in   870 repeats    0.00 % in 0 genes
15   529994  chr2  NT_022135.16  36208774-36738768    45.63 % in   779 repeats    0.00 % in 0 genes
16   527971  chr20  NT_011362.10  10274174-10802145    55.18 % in   1071 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
1016518  chr12  NT_029419.12  36144301-37160819    1655  359       AT_rich (175)  L2a (53)  (TA)n (47) 
824351  chrX  NT_011651.17  787845-1612196    1042  218       L2c (52)  MIRb (50)  AT_rich (43) 
696592  chr6  NT_025741.15  6808601-7505193    1088  272       AT_rich (165)  (TA)n (34)  MIR (23) 
609742  chr5  NT_023133.13  10123324-10733066    1012  262       AT_rich (73)  AluSx (53)  MIRb (44) 
609400  chr4  NT_006238.11  5673403-6282803    977  247       AT_rich (114)  MIR (59)  L2a (47) 
589458  chr1  NT_004487.19  25777141-26366599    1017  218       AT_rich (77)  AluSx (77)  MIRb (38) 
582842  chr3  NT_005612.16  72425828-73008670    900  244       AT_rich (114)  AluSx (25)  MIR (22) 
571106  chr3  NT_005612.16  71359277-71930383    968  256       AT_rich (104)  L2a (33)  MIRb (31) 
566260  chr15  NT_037852.6  1339256-1905516    164  72       L1MDa (10)  (CAGGG)n (8)  AT_rich (7) 
10  561568  chr6  NT_025741.15  44836994-45398562    929  238       AT_rich (89)  AluSx (26)  MIR (23) 
11  545960  chr2  NT_005403.17  37121352-37667312    906  247       AT_rich (71)  MIRb (27)  AluSx (27) 
12  542922  chr10  NT_030059.13  60464560-61007482    870  243       MIRb (63)  AT_rich (50)  MIR (33) 
13  540922  chr12  NT_029419.12  62146475-62687397    1087  241       AluSx (80)  AT_rich (66)  L2c (48) 
14  531120  chr6  NT_007299.13  9995305-10526425    870  243       AT_rich (67)  MIR (36)  L2a (33) 
15  529994  chr2  NT_022135.16  36208774-36738768    779  215       AT_rich (82)  MIRb (30)  MIR (28) 
16  527971  chr20  NT_011362.10  10274174-10802145    1071  254       MIRb (68)  AluSx (51)  MIR (47) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
1   1016518       chr12  NT_029419.12  36144301-37160819    RPL31P48 
LOC100128674  hypothetical_protein_LOC100507377
VENTXP3 
ATXN7L3B  ataxin_7-like_3B
2   824351       chrX  NT_011651.17  787845-1612196    CYSLTR1  cysteinyl_leukotriene_receptor_1
ZCCHC5  zinc_finger_CCHC_domain-containing_protein_5
LOC100421601 
LPAR4  lysophosphatidic_acid_receptor_4
RPL7P54 
MIR4328  microRNA_4328
P2RY10  putative_P2Y_purinoceptor_10
4   609742       chr5  NT_023133.13  10123324-10733066    RPL21P59 
RPL7P20 
RPLP0P9 
5   609400       chr4  NT_006238.11  5673403-6282803    GABRG1  gamma-aminobutyric_acid_receptor_subunit_gamma-1_precursor
GABRA2  gamma-aminobutyric_acid_receptor_subunit_alpha-2_precursor
6   589458       chr1  NT_004487.19  25777141-26366599    RPS26P12  rab_GTPase-activating_protein_1-like_isoform_B
7   582842       chr3  NT_005612.16  72425828-73008670    LOC100287630 
8   571106       chr3  NT_005612.16  71359277-71930383    SLITRK3  SLIT_and_NTRK-like_protein_3_precursor



Posfai@neb.com
May 11, 2011