Distribution of restriction sites in the human genome

Enzyme:  Mva1269I               Longest uncut segments
Specificity:  GAATGC               Repeats in uncut segments
Number of sites:  1226740               Genes in uncut segments
Mean distance between sites:  2332 base pairs
Standard deviation:  2479 base pairs
Site density 428.7 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   492621  chr15  NT_037852.6  1395230-1887851    0.33 % in   9 repeats    0.00 % in 0 genes
2   404391  chr6  NT_167244.1  2356935-2761326    0.55 % in   9 repeats    0.00 % in 0 genes
3   210792  chr6  NT_167244.1  4389135-4599927    1.06 % in   12 repeats    0.00 % in 0 genes
4   185976  chr6  NT_167244.1  3169753-3355729    2.93 % in   38 repeats    5.63 % in 1 genes
5   181802  chr6  NT_167244.1  3790067-3971869    0.76 % in   7 repeats    0.00 % in 0 genes
6   173288  chr6  NT_167247.1  4421576-4594864    0.35 % in   2 repeats    100.00 % in 1 genes
7   168758  chr6  NT_167249.1  2135338-2304096    1.70 % in   15 repeats    0.00 % in 0 genes
8   167775  chr6  NT_167247.1  1560223-1727998    1.31 % in   10 repeats    1.63 % in 1 genes
9   161656  chr6  NT_167248.1  521888-683544    1.45 % in   2 repeats    0.00 % in 0 genes
10   157153  chr6  NT_167244.1  2007936-2165089    0.76 % in   5 repeats    0.00 % in 0 genes
11   152743  chr6  NT_167244.1  2888125-3040868    5.20 % in   42 repeats    0.00 % in 0 genes
12   151553  chr9  NT_008470.19  21692022-21843575    0.58 % in   3 repeats    0.00 % in 0 genes
13   143437  chrY  NT_011875.12  8491885-8635322    65.09 % in   6 repeats    0.00 % in 0 genes
14   123226  chr6  NT_167246.1  3257501-3380727    2.34 % in   17 repeats    0.00 % in 0 genes
15   120751  chr6  NT_167247.1  1175814-1296565    1.77 % in   5 repeats    0.00 % in 0 genes
16   119522  chr6  NT_167245.1  2605381-2724903    1.66 % in   4 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
492621  chr15  NT_037852.6  1395230-1887851    9       MLT1L (1)  MIRc (1)  MIRb (1) 
404391  chr6  NT_167244.1  2356935-2761326    7       L4 (2)  AluJb (2)  MER8 (1) 
210792  chr6  NT_167244.1  4389135-4599927    12  10       MER57-int (2)  AluSx (2)  (TTCC)n (1) 
185976  chr6  NT_167244.1  3169753-3355729    38  21       AluSx (5)  L1MC5 (4)  L1MB3 (4) 
181802  chr6  NT_167244.1  3790067-3971869    6       MLT1H-int (2)  MER52D (1)  LTR19B (1) 
173288  chr6  NT_167247.1  4421576-4594864    2       MER11A (1)  AluSc (1) 
168758  chr6  NT_167249.1  2135338-2304096    15  8       AluSx (4)  L1MB8 (3)  MLT1A (2) 
167775  chr6  NT_167247.1  1560223-1727998    10  8       Tigger7 (2)  MIR (2)  MIRc (1) 
161656  chr6  NT_167248.1  521888-683544    2       L1PREC2 (1)  HERVH-int (1) 
10  157153  chr6  NT_167244.1  2007936-2165089    4       AluSx (2)  MIRb (1)  MIR (1) 
11  152743  chr6  NT_167244.1  2888125-3040868    42  20       L1MC5 (6)  AluY (5)  AluSc (4) 
12  151553  chr9  NT_008470.19  21692022-21843575    2       LTR67B (2)  L1M5 (1) 
13  143437  chrY  NT_011875.12  8491885-8635322    2       LTR12B (5)  LTR12D (1) 
14  123226  chr6  NT_167246.1  3257501-3380727    17  12       L1MC5 (3)  AluSx (3)  MIRb (2) 
15  120751  chr6  NT_167247.1  1175814-1296565    4       ERV3-16A3_I-int (2)  L3 (1)  L2a (1) 
16  119522  chr6  NT_167245.1  2605381-2724903    3       L2 (2)  MLT1E2 (1)  L2a (1) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
4   185976       chr6  NT_167244.1  3169753-3355729    EHMT2  histone-lysine_N-methyltransferase,_H3_lysine-9_specific_3_isoform_b
6   173288       chr6  NT_167247.1  4421576-4594864    LOC100507722  hypothetical_protein_LOC100507722
8   167775       chr6  NT_167247.1  1560223-1727998    LOC100421582  tripartite_motif-containing_protein_26



Posfai@neb.com
May 11, 2011