Distribution of restriction sites in the human genome

Enzyme:  SstE37I               Longest uncut segments
Specificity:  CGAAGAC               Repeats in uncut segments
Number of sites:  43249               Genes in uncut segments
Mean distance between sites:  66159 base pairs
Standard deviation:  70539 base pairs
Site density 15.1 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   957253  chr1  NT_032977.9  40714432-41671685    54.86 % in   1721 repeats    37.25 % in 8 genes
2   884803  chr6  NT_007592.15  50091879-50976682    42.96 % in   1300 repeats    10.42 % in 6 genes
3   804405  chr2  NT_005403.17  64966820-65771225    48.71 % in   1294 repeats    84.79 % in 2 genes
4   689740  chr13  NT_024524.14  41491434-42181174    46.84 % in   1218 repeats    59.58 % in 3 genes
5   680937  chr14  NT_026437.12  27939357-28620294    46.07 % in   1057 repeats    47.54 % in 3 genes
6   676324  chr13  NT_024524.14  42786908-43463232    55.61 % in   1073 repeats    0.86 % in 1 genes
7   672874  chr6  NT_007299.13  4871496-5544370    57.66 % in   1039 repeats    0.71 % in 2 genes
8   671309  chr19  NT_011295.11  12463149-13134458    70.92 % in   1448 repeats    45.51 % in 15 genes
9   645192  chr4  NT_016354.19  24006035-24651227    56.52 % in   1252 repeats    0.00 % in 0 genes
10   644275  chr6  NT_007299.13  19744367-20388642    57.74 % in   985 repeats    0.00 % in 0 genes
11   620016  chr7  NT_007933.15  20295536-20915552    41.15 % in   923 repeats    0.00 % in 0 genes
12   618902  chr3  NT_005612.16  86362993-86981895    55.94 % in   1056 repeats    0.00 % in 0 genes
13   615887  chr12  NT_009775.17  3387152-4003039    59.93 % in   1695 repeats    0.00 % in 0 genes
14   610852  chr4  NT_022778.16  10313239-10924091    58.35 % in   905 repeats    0.00 % in 0 genes
15   608698  chr13  NT_024524.14  47616687-48225385    36.66 % in   863 repeats    0.00 % in 0 genes
16   606591  chr4  NT_006316.16  17801412-18408003    52.12 % in   1088 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
957253  chr1  NT_032977.9  40714432-41671685    1721  339       AT_rich (101)  AluSx (101)  MIRb (94) 
884803  chr6  NT_007592.15  50091879-50976682    1300  274       AT_rich (118)  MIR (61)  MIRb (59) 
804405  chr2  NT_005403.17  64966820-65771225    1294  298       AT_rich (108)  L2a (55)  MIR (49) 
689740  chr13  NT_024524.14  41491434-42181174    1218  286       AT_rich (87)  AluSx (70)  L2a (53) 
680937  chr14  NT_026437.12  27939357-28620294    1057  268       AT_rich (142)  L2a (42)  MIR (41) 
676324  chr13  NT_024524.14  42786908-43463232    1073  290       AT_rich (134)  L2a (33)  L2 (31) 
672874  chr6  NT_007299.13  4871496-5544370    1039  282       AT_rich (133)  (TA)n (30)  L2a (30) 
671309  chr19  NT_011295.11  12463149-13134458    1448  183       AluSx (142)  AluSg (90)  AluSp (80) 
645192  chr4  NT_016354.19  24006035-24651227    1252  292       AluSx (82)  AT_rich (63)  AluJo (50) 
10  644275  chr6  NT_007299.13  19744367-20388642    985  237       AT_rich (100)  (TA)n (30)  MIRb (27) 
11  620016  chr7  NT_007933.15  20295536-20915552    923  251       AT_rich (124)  MIR (33)  MIRb (31) 
12  618902  chr3  NT_005612.16  86362993-86981895    1056  254       AT_rich (73)  MIRb (54)  L2a (41) 
13  615887  chr12  NT_009775.17  3387152-4003039    1695  261       AluSx (155)  MIR (130)  MIRb (116) 
14  610852  chr4  NT_022778.16  10313239-10924091    905  228       AT_rich (112)  MIR (25)  L1ME3A (20) 
15  608698  chr13  NT_024524.14  47616687-48225385    863  234       AT_rich (118)  L2a (35)  MIRb (33) 
16  606591  chr4  NT_006316.16  17801412-18408003    1088  255       AT_rich (69)  L2a (59)  L2c (56) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
1   957253       chr1  NT_032977.9  40714432-41671685    ANKRD13C  ankyrin_repeat_domain-containing_protein_13C
HHLA3  HERV-H_LTR-associating_protein_3_isoform_3
CTH  cystathionine_gamma-lyase_isoform_3
LOC391048 
LOC100131616 
PTGER3  prostaglandin_E2_receptor_EP3_subtype_isoform_5
LOC100132618  hypothetical_LOC100132618
MIR186  microRNA:hsa-mir-186
2   884803       chr6  NT_007592.15  50091879-50976682    TFAP2D  transcription_factor_AP-2-delta
TFAP2B  transcription_factor_AP-2-beta
RPS17P5 
LOC100418898 
FTH1P5 
LOC100421020 
3   804405       chr2  NT_005403.17  64966820-65771225    RPL5P8  sperm-associated_antigen_16_protein_isoform_2
VWC2L  von_Willebrand_factor_C_domain-containing_protein_2-like_precursor
4   689740       chr13  NT_024524.14  41491434-42181174    DIAPH3  protein_diaphanous_homolog_3_isoform_b
LOC440142 
TDRD3  tudor_domain-containing_protein_3_isoform_2
5   680937       chr14  NT_026437.12  27939357-28620294    LOC100506412  hypothetical_LOC100506412
RPL10L  60S_ribosomal_protein_L10-like
RPS15AP3  MAM_domain-containing_glycosylphosphatidylinositol_anchor_protein_2_isoform_2
6   676324       chr13  NT_024524.14  42786908-43463232    PCDH20  protocadherin-20
7   672874       chr6  NT_007299.13  4871496-5544370    NUFIP1P 
LOC100420940 
8   671309       chr19  NT_011295.11  12463149-13134458    ZNF430  zinc_finger_protein_430_isoform_2
VN1R80P 
VN1R81P  zinc_finger_protein_714
RPL7AP10  zinc_finger_protein_431
VN1R82P 
RPL36AP51 
VN1R83P 
LOC100421707  zinc_finger_protein_708
LOC100422298  zinc_finger_protein_738
ZNF493  zinc_finger_protein_493_isoform_1
LOC400680  hypothetical_LOC400680
LOC100421699  zinc_finger_protein_429
LOC100505594  hypothetical_LOC100505594
LOC400682  zinc_finger_protein_100
LOC100418832 



Posfai@neb.com
May 11, 2011