Distribution of restriction sites in the human genome

Enzyme:  NlaCI               Longest uncut segments
Specificity:  CATCAC               Repeats in uncut segments
Number of sites:  1572017               Genes in uncut segments
Mean distance between sites:  1820 base pairs
Standard deviation:  1944 base pairs
Site density 549.4 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   487205  chr15  NT_037852.6  1398428-1885633    0.01 % in   1 repeats    0.00 % in 0 genes
2   404089  chr6  NT_167244.1  2358241-2762330    0.35 % in   6 repeats    0.00 % in 0 genes
3   212933  chr6  NT_167244.1  4387976-4600909    1.86 % in   14 repeats    0.00 % in 0 genes
4   189449  chr6  NT_167244.1  3790274-3979723    3.10 % in   24 repeats    0.00 % in 0 genes
5   177759  chr6  NT_167244.1  3179242-3357001    0.43 % in   7 repeats    1.01 % in 2 genes
6   172760  chr6  NT_167247.1  4421678-4594438    0.11 % in   2 repeats    100.00 % in 1 genes
7   168281  chr6  NT_167249.1  2138155-2306436    1.69 % in   14 repeats    0.00 % in 0 genes
8   167832  chr6  NT_167247.1  1560423-1728255    1.19 % in   10 repeats    1.51 % in 1 genes
9   163015  chr6  NT_167248.1  521614-684629    2.27 % in   2 repeats    0.00 % in 0 genes
10   159703  chr6  NT_167244.1  2006125-2165828    1.19 % in   9 repeats    0.00 % in 0 genes
11   151902  chr9  NT_008470.19  21692551-21844453    0.48 % in   3 repeats    0.00 % in 0 genes
12   144102  chr6  NT_167244.1  2893717-3037819    0.52 % in   6 repeats    0.00 % in 0 genes
13   118937  chr6  NT_167245.1  2605389-2724326    1.18 % in   3 repeats    0.00 % in 0 genes
14   116961  chr6  NT_167247.1  1177314-1294275    0.30 % in   1 repeats    0.00 % in 0 genes
15   116241  chr6  NT_167246.1  3259401-3375642    0.56 % in   4 repeats    0.00 % in 0 genes
16   115320  chr6  NT_167245.1  135217-250537    4.71 % in   14 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
487205  chr15  NT_037852.6  1398428-1885633    1       AT_rich (1) 
404089  chr6  NT_167244.1  2358241-2762330    5       AluJb (2)  L4 (1)  L1ME4a (1) 
212933  chr6  NT_167244.1  4387976-4600909    14  11       MER57-int (2)  AluSx (2)  AluSg/x (2) 
189449  chr6  NT_167244.1  3790274-3979723    24  18       L2a (5)  MLT1H-int (2)  L1M5 (2) 
177759  chr6  NT_167244.1  3179242-3357001    5       GC_rich (3)  Charlie4a (1)  (CCG)n (1) 
172760  chr6  NT_167247.1  4421678-4594438    2       MER11A (1)  AluSc (1) 
168281  chr6  NT_167249.1  2138155-2306436    14  6       Charlie2b (4)  AluSx (4)  L1MB8 (3) 
167832  chr6  NT_167247.1  1560423-1728255    10  8       Tigger7 (2)  MIR (2)  MIRc (1) 
163015  chr6  NT_167248.1  521614-684629    2       L1PREC2 (1)  HERVH-int (1) 
10  159703  chr6  NT_167244.1  2006125-2165828    6       AluSx (4)  MIRb (1)  MIR (1) 
11  151902  chr9  NT_008470.19  21692551-21844453    3       MIR3 (1)  LTR67B (1)  L1M5 (1) 
12  144102  chr6  NT_167244.1  2893717-3037819    6       (TCC)n (1)  L1MC5 (1)  AluY (1) 
13  118937  chr6  NT_167245.1  2605389-2724326    3       MLT1E2 (1)  L2a (1)  L2 (1) 
14  116961  chr6  NT_167247.1  1177314-1294275    1       ERV3-16A3_I-int (1) 
15  116241  chr6  NT_167246.1  3259401-3375642    3       MIRb (2)  MIR3 (1)  AluSx (1) 
16  115320  chr6  NT_167245.1  135217-250537    14  13       L2c (2)  (TTTC)n (1)  MLT1F (1) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
5   177759       chr6  NT_167244.1  3179242-3357001    EHMT2  histone-lysine_N-methyltransferase,_H3_lysine-9_specific_3_isoform_b
TNXB  tenascin-X_isoform_1_precursor
6   172760       chr6  NT_167247.1  4421678-4594438    LOC100507722  hypothetical_protein_LOC100507722
8   167832       chr6  NT_167247.1  1560423-1728255    LOC100421582  tripartite_motif-containing_protein_26



Posfai@neb.com
May 11, 2011