Distribution of restriction sites in the human genome

Enzyme:  AleI               Longest uncut segments
Specificity:  CACNNNNGTG               Repeats in uncut segments
Number of sites:  534287               Genes in uncut segments
Mean distance between sites:  5355 base pairs
Standard deviation:  6183 base pairs
Site density 186.7 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   497514  chr15  NT_037852.6  1394349-1891863    1.07 % in   23 repeats    0.00 % in 0 genes
2   405647  chr6  NT_167244.1  2359092-2764739    0.31 % in   6 repeats    0.00 % in 0 genes
3   212165  chr6  NT_167244.1  4387571-4599736    1.79 % in   12 repeats    0.00 % in 0 genes
4   184935  chr6  NT_167244.1  3788289-3973224    1.55 % in   17 repeats    0.00 % in 0 genes
5   183765  chr6  NT_167244.1  3174447-3358212    2.65 % in   30 repeats    4.25 % in 2 genes
6   176468  chr6  NT_167247.1  4418264-4594732    0.69 % in   7 repeats    100.00 % in 1 genes
7   171279  chr6  NT_167247.1  1556597-1727876    2.57 % in   22 repeats    3.71 % in 1 genes
8   169418  chr6  NT_167249.1  2134662-2304080    1.81 % in   16 repeats    0.00 % in 0 genes
9   168062  chr6  NT_167245.1  98389-266451    23.71 % in   127 repeats    0.00 % in 0 genes
10   162763  chr7  NT_023603.5  34135-196898    100.00 % in   4 repeats    0.00 % in 0 genes
11   162198  chr6  NT_167248.1  521447-683645    1.78 % in   2 repeats    0.00 % in 0 genes
12   160217  chr6  NT_167244.1  2888000-3048217    5.36 % in   45 repeats    0.00 % in 0 genes
13   153506  chr9  NT_008470.19  21691301-21844807    1.09 % in   7 repeats    0.00 % in 0 genes
14   143437  chrY  NT_011875.12  8491489-8634926    65.09 % in   6 repeats    0.00 % in 0 genes
15   134688  chr6  NT_167246.1  3245186-3379874    5.98 % in   50 repeats    0.00 % in 0 genes
16   127149  chr6  NT_167245.1  2600436-2727585    5.72 % in   20 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
497514  chr15  NT_037852.6  1394349-1891863    23  19       L2a (3)  L1MDa (2)  L1M5 (2) 
405647  chr6  NT_167244.1  2359092-2764739    6       LTR84b (1)  L4 (1)  L1MEg (1) 
212165  chr6  NT_167244.1  4387571-4599736    12  10       MER57-int (2)  AluSx (2)  (TTCC)n (1) 
184935  chr6  NT_167244.1  3788289-3973224    17  14       MLT1H-int (2)  L2a (2)  AT_rich (2) 
183765  chr6  NT_167244.1  3174447-3358212    30  16       AluSx (6)  L1MB3 (4)  GC_rich (3) 
176468  chr6  NT_167247.1  4418264-4594732    7       MIRb (1)  MIR (1)  MER11A (1) 
171279  chr6  NT_167247.1  1556597-1727876    22  17       L2c (3)  Tigger7 (2)  MSTD (2) 
169418  chr6  NT_167249.1  2134662-2304080    16  9       AluSx (4)  L1MB8 (3)  MLT1A (2) 
168062  chr6  NT_167245.1  98389-266451    127  58       AluSx (13)  AluY (11)  AluSg (6) 
10  162763  chr7  NT_023603.5  34135-196898    2       L1PA2 (2)  ALR/Alpha (2) 
11  162198  chr6  NT_167248.1  521447-683645    2       L1PREC2 (1)  HERVH-int (1) 
12  160217  chr6  NT_167244.1  2888000-3048217    45  21       L1MC5 (6)  AluY (5)  AluSc (4) 
13  153506  chr9  NT_008470.19  21691301-21844807    5       LTR67B (2)  L2 (2)  MSTA (1) 
14  143437  chrY  NT_011875.12  8491489-8634926    2       LTR12B (5)  LTR12D (1) 
15  134688  chr6  NT_167246.1  3245186-3379874    50  27       AluSx (11)  MIRb (3)  L1MC5 (3) 
16  127149  chr6  NT_167245.1  2600436-2727585    20  16       Tigger1 (2)  MLT1N2 (2)  MER21C (2) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
5   183765       chr6  NT_167244.1  3174447-3358212    EHMT2  histone-lysine_N-methyltransferase,_H3_lysine-9_specific_3_isoform_b
TNXB  tenascin-X_isoform_1_precursor
6   176468       chr6  NT_167247.1  4418264-4594732    LOC100507722  hypothetical_protein_LOC100507722
7   171279       chr6  NT_167247.1  1556597-1727876    LOC100421582  tripartite_motif-containing_protein_26



Posfai@neb.com
May 11, 2011