Distribution of restriction sites in the human genome

Enzyme:  LlaCI               Longest uncut segments
Specificity:  AAGCTT               Repeats in uncut segments
Number of sites:  837343               Genes in uncut segments
Mean distance between sites:  3417 base pairs
Standard deviation:  3640 base pairs
Site density 292.6 per megabase               Help


Distribution of closely spaced sites

Distribution of sites within 7 STD distance


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Longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeat content Gene content
1   500697  chr15  NT_037852.6  1393200-1893897    1.42 % in   27 repeats    0.16 % in 1 genes
2   407587  chr6  NT_167244.1  2355352-2762939    0.93 % in   18 repeats    0.00 % in 0 genes
3   210612  chr6  NT_167244.1  4389158-4599770    1.05 % in   12 repeats    0.00 % in 0 genes
4   195013  chr6  NT_167244.1  3786209-3981222    3.85 % in   32 repeats    0.66 % in 1 genes
5   180367  chr6  NT_167244.1  3178369-3358736    1.25 % in   12 repeats    2.44 % in 2 genes
6   179380  chr6  NT_167247.1  1549978-1729358    4.61 % in   42 repeats    7.23 % in 1 genes
7   179335  chr6  NT_167247.1  4418903-4598238    1.98 % in   16 repeats    100.00 % in 1 genes
8   177089  chr6  NT_167244.1  2867370-3044459    11.38 % in   103 repeats    6.15 % in 4 genes
9   175300  chr6  NT_167249.1  2127964-2303264    3.37 % in   25 repeats    0.00 % in 0 genes
10   164726  chr6  NT_167248.1  518020-682746    3.29 % in   2 repeats    0.00 % in 0 genes
11   163734  chr9  NT_008470.19  21686268-21850002    4.21 % in   24 repeats    0.00 % in 0 genes
12   157046  chr6  NT_167244.1  2009295-2166341    0.03 % in   1 repeats    0.00 % in 0 genes
13   150818  chrY  NT_011875.12  8480867-8631685    66.80 % in   6 repeats    0.00 % in 0 genes
14   129481  chr6  NT_167249.1  3363080-3492561    18.14 % in   114 repeats    0.00 % in 0 genes
15   128883  chr6  NT_167245.1  2598286-2727169    7.15 % in   22 repeats    0.00 % in 0 genes
16   128439  chr6  NT_167246.1  3258374-3386813    4.28 % in   26 repeats    0.00 % in 0 genes


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Repeats in longest uncut segments
# Length  Chr  Scaffold  Coordinates  Repeats
Total  Distinct    Most  Second  Third 
500697  chr15  NT_037852.6  1393200-1893897    27  20       L2a (3)  L1MDa (3)  MER44C (2) 
407587  chr6  NT_167244.1  2355352-2762939    18  11       L1ME4a (3)  AluJb (3)  MLT2D (2) 
210612  chr6  NT_167244.1  4389158-4599770    12  10       MER57-int (2)  AluSx (2)  (TTCC)n (1) 
195013  chr6  NT_167244.1  3786209-3981222    32  24       L2a (6)  MLT1H-int (2)  L1M5 (2) 
180367  chr6  NT_167244.1  3178369-3358736    12  8       GC_rich (3)  L2c (2)  AluSp (2) 
179380  chr6  NT_167247.1  1549978-1729358    42  27       MIRc (3)  MIR3 (3)  L2c (3) 
179335  chr6  NT_167247.1  4418903-4598238    16  14       MLT1J (2)  AluSx (2)  (TTAAA)n (1) 
177089  chr6  NT_167244.1  2867370-3044459    103  34       AluSx (14)  AluJo (12)  AluY (8) 
175300  chr6  NT_167249.1  2127964-2303264    25  15       MamGypLTR1b (3)  AluJo (3)  MLT2B1 (2) 
10  164726  chr6  NT_167248.1  518020-682746    2       L1PREC2 (1)  HERVH-int (1) 
11  163734  chr9  NT_008470.19  21686268-21850002    24  16       MIRb (2)  MER5B (2)  LTR67B (2) 
12  157046  chr6  NT_167244.1  2009295-2166341    1       MIRb (1) 
13  150818  chrY  NT_011875.12  8480867-8631685    2       LTR12B (5)  LTR12D (1) 
14  129481  chr6  NT_167249.1  3363080-3492561    114  43       AluSx (20)  L2a (7)  AluY (7) 
15  128883  chr6  NT_167245.1  2598286-2727169    22  18       Tigger1 (2)  MLT1N2 (2)  MER21C (2) 
16  128439  chr6  NT_167246.1  3258374-3386813    26  18       AluSx (4)  L1MC5 (3)  MIRb (2) 


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Genes in longest uncut segments
Sgmnt   Length (bp)  Chr  Scaffold  Coordinates  Gene symbol  Gene function 
1   500697       chr15  NT_037852.6  1393200-1893897    LOC100418897 
4   195013       chr6  NT_167244.1  3786209-3981222    HLA-DRB3  major_histocompatibility_complex,_class_II,_DR_beta_3_precursor
5   180367       chr6  NT_167244.1  3178369-3358736    EHMT2  histone-lysine_N-methyltransferase,_H3_lysine-9_specific_3_isoform_b
TNXB  tenascin-X_isoform_1_precursor
6   179380       chr6  NT_167247.1  1549978-1729358    LOC100421582  tripartite_motif-containing_protein_26
7   179335       chr6  NT_167247.1  4418903-4598238    LOC100507722  hypothetical_protein_LOC100507722
8   177089       chr6  NT_167244.1  2867370-3044459    LST1  leukocyte-specific_transcript_1_protein_isoform_5
NCR3  natural_cytotoxicity_triggering_receptor_3_isoform_c
UQCRHP1 
MSH5  mutS_protein_homolog_5_isoform_c



Posfai@neb.com
May 11, 2011